Madv Info Sheet

Listing Results Madv Info Sheet

Frequently Asked Questions

• What is the structure of the MADV capsid?

  The MADV virion capsid surrounds the viral core and is composed of major (penton, hexon, fiber) and minor (pIX, pIIIa, pVI and pVIII) [1,11] capsid proteins (Figure 1B), which play important roles in stabilizing the virion structure involving protein–protein interactions [1]. 2. MADV Core Proteins

• What are the core proteins of MADV?

  2. MADV Core Proteins The viral core of icosahedral DNA and RNA viruses consists of proteins associated with nucleic acids. The core of MADV contains genomic DNA and core proteins pVII, pV, Mu(pX), pIVa2, terminal protein (TP) and AdV encoded protease (Figure 1) [1,11].

• What is the pathophysiology of mouse adenovirus infection?

  There are two strains of mouse adenovirus: MADV-1 and MADV-2. MADV-1 is transmitted through direct contact with urine, feces, or nasal secretions. MADV-2 infects the intestinal tract and is excreted for at least 3 weeks in immunocompetent mice. Seroconversion to MADV-2 is noted in some rat colonies, but this is probably a different virus.

• When can I get my marksheet from Madhav University?

  NOTICE: This is to inform you that all the passed out students of Madhav University could collect their Marksheet, Provisional Degree, Character Certificate, Migration Certificate, etc. of Bachelor's, Master's & All Courses before 31 August,2021.

• What is the pathophysiology of mouse adenovirus infection?

  There are two strains of mouse adenovirus: MADV-1 and MADV-2. MADV-1 is transmitted through direct contact with urine, feces, or nasal secretions. MADV-2 infects the intestinal tract and is excreted for at least 3 weeks in immunocompetent mice. Seroconversion to MADV-2 is noted in some rat colonies, but this is probably a different virus.

• What is Adenovirus used for in gene therapy?

  Adenovirus is another important type of viral vector that is used in human gene therapy ( 6 ). Unlike retrovirus vectors, which can infect only dividing cells, adenovirus has relatively high transduction efficiency in target cells and infects both dividing and nondividing cells ( 6 ).

• Does the adenovirus vector integrate into the germ line?

  No evidence of germ-line integration of adenovirus vector could be found in offspring from infected stem cells that underwent Cre-mediated recombination, which suggests that the adenovirus vector infected the cells but did not stably integrate into the germ line.

• Is there a role for adenovirus-mediated Cre expression in spermatogonial stem cells?

  In this sense, adenovirus-mediated Cre expression in spermatogonial stem cells may be useful. By transplanting transgenically marked cells, it is possible to visualize the pattern and kinetics of the repopulation process from single stem cells ( 27 ), which can reveal abnormal functions that are not evident in physiological conditions.