NANOTemper - Tools for Challenging Biophysical Characterizations Tools for your most challenging characterizations Get biophysical tools for your drug discovery and basic science research Prometheus Panta adds DLS to the new gold standard for challenging stability characterization Learn more
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Proteins with a higher T m are more stable because a greater input of energy is required to reach the unfolding transition. Because Tm is an accurate and established metric for assessing protein stability, it’s an essential parameter to determine. T onset. The detectable temperature at which a protein begins to unfold.
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Prometheus NT.Plex - manual loading. The capillary chips can easily be filled by capillary action with your sample prepared in 384-well plates without any further manual pipetting or loading steps. The Prometheus NT.Plex instrument is based on NANODSF technology for easy, rapid and accurate analysis of protein folding and stability.
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Webinar. How to improve outcomes of your viral vectors for gene therapy with high-quality data from biophysical profiling methods. Optimizing your vectors for gene therapy is a daunting task. When developing and optimizing AAVs, concerns such as serotype, storage stability, expression method, and genetic fill level must be addres.
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Here we demonstrate that the Prometheus NT.Plex by NANOTemper Technologies can be used for long-term stability prediction of biologics using …
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Description. The premium package includes a Tycho NT.6, software, Tycho NT.6 starter kit (3 vials of capillaries), power supply, power supply holder, USB memory stick, user manual, quick start guide, a 2-year warranty, and installation & training via WebEx. For use with.
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Tycho NT.6. SKU: TY-002. €30,668.00 excl VAT. New price: Add to Cart. The quantity you have chosen is in between 2 base units () Minimum quantity requirements for product are not fulfilled. Maximum quantity requirements for product are not fulfilled.
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NANOTemper retails two popular MST technologies, one requiring a fluorescent tag and another based on using inherent fluorescence of proteins due to presence of aromatic residues . One major disadvantage of label-free thermophoresis is that it does not allow for the measurement of protein-protein interactions unless one of the proteins to be measured does not contain …
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NANO Temper Monolith NT.115 User Manual Operation & user’s manual (24 pages) Agilent Technologies Mx3000P Setup And User Manual Setup and user manual (43 pages) Industrial Scientific MX6 iBrid Quick Start Quick start (2 pages)
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NANOTemper Technologies offers NANODSF technology with the Prometheus Series. NANODSF is the method of choice for easy, rapid and accurate analysis of protein stability and aggregation, with applications in protein engineering, membrane protein research, formulation development and quality control.
Contact NANOTemper Technologies service personnel if you need to open the instrument. CAUTION Use of controls or adjustments or performance of procedures other than those specified herein may result in hazardous invisible radiation exposure.
NANOTemper launches Andromeda, helping Biopharma and CROs to increase efficiency of expression screening for membrane proteins SOUTH SAN FRANCISCO, Calif. June 24, 2021 — NANOTemper Technologies, well-known for creating biophysical tools that tackle challenging characterizations, enters the protein production market with...
NANOTemper tools are the quickest way to characterize proteins and perform protein sequence analysis for research in pharmaceutical, biotechnology and academia. Your choice regarding cookies on this site
Most software starts once you load your samples and start your run. Monolith’s MO.Control is built differently — not only do you get help with guided step-by-step experimental planning and assay setup before you start your run, but you also get immediate feedback on assay optimization based on your results after the run is over.
Monolith gives you one less thing to worry about because it has the flexibility to handle all different types of molecules and samples. Monolith uses MST technology to quantify molecular interactions between a target and ligand by detecting changes in fluorescence intensity while a temperature gradient is applied over time (grey box, top figure).
With Monolith, you get a K d in a fraction of the volume and concentration, leaving you with more sample for additional experiments. Immobilizing molecules in SPR assays often causes them to lose activity, and you’re left without results.
Monolith uses MST technology to quantify molecular interactions between a target and ligand by detecting changes in fluorescence intensity while a temperature gradient is applied over time (grey box, top figure).