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What promotes cancer

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Cancer and Diet 101: How What You Eat Can Influence Cancer

Cancer is one of the leading causes of death worldwide ().But studies suggest that simple lifestyle changes, such as following a healthy diet, could prevent 30–50% of all cancers (2, 3).Growing ...

Active: 2021-03-02

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FTO modifies the m6A level of MALAT and promotes bladder ...

A high expression of FTO is detected in tumor tissue and is clinically related to the pathological traits of bladder cancer, suggesting that FTO is a potential biomarker for either the diagnosis or clinical prediction of bladder cancer. Moreover, FTO promotes the tumorigenicity of bladder cancer, specifically stimulating tumor growth in vivo ...

Active: 2021-02-28

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Nicotine promotes breast cancer metastasis by stimulating ...

Smoking has a profound impact on tumor immunity, and nicotine, which is the major addictive component of smoke, is known to promote tumor progression despite being a non-carcinogen. In this study ...

Active: 2021-02-28

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Deubiquitinase OTUD6A promotes proliferation of cancer ...

However, the regulation of Drp1, especially of its ubiquitination, remains unclear. In this study, we report that the ovarian tumor‐associated protease deubiquitinase 6A (OTUD6A) deubiquitylates and stabilizes Drp1, thereby facilitating regulation of mitochondrial morphology and tumorigenesis.

Active: 2021-03-01

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Exosomal circPACRGL promotes ... - Molecular Cancer

Colorectal cancer (CRC) is the leading cause of cancer-related death worldwide. Exosome shave emerged as crucial regulators of intercellular communication and that abundant Circular RNAs (circRNAs) are enriched within exosomes. CircRNAs are novel members of noncoding RNAs regulating cancer proliferation and progression. However, the function and regulatory mechanism of cancer-derived exosomal ...

Active: 2021-03-02

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KIF11 promotes cell proliferation via ERBB2/PI3K/AKT ...

Monastrol induced G2M arrest and proliferation inhibition via downregulation of the ERBB2/PI3K/AKT signaling pathway. (A) The cell growth curve of NOZ and EH-GB1 exposed to different concentration Monastrol (0, 5, 10, 15, 20 μM) for different lengths of time (0h, 24h, 48h, 72h).

Active: 2021-03-02

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Porphyromonas gingivalis promotes progression of ...

Microbial dysbiosis in the upper digestive tract is linked to an increased risk of esophageal squamous cell carcinoma (ESCC); this study shows that invasion of the bacterium Porphyromonas gingivalis enhances the aggressive progression of ESCC via the TGFβ/Smad and TGFβ/YAP/TAZ pathways. Targeting P. gingivalis or its activated effectors may provide novel avenues into clinical management of ESCC.

Active: 2020-10-09

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Stromal Platelet–Derived Growth Factor ... - Cancer Research

Platelet-derived growth factor receptor-beta (PDGFRβ) is a receptor tyrosine kinase found in cells of mesenchymal origin such as fibroblasts and pericytes. Activation of this receptor is dependent on paracrine ligand induction, and its preferred ligand PDGFB is released by neighboring epithelial and endothelial cells. While expression of both PDGFRβ and PDGFB has been noted in patient breast ...

Active: 2021-03-01

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Frontiers | PVT1 Promotes Cancer Progression via MicroRNAs ...

Non-coding RNA (ncRNA) plays a regulatory role in a variety of cellular activities. And long non-coding RNA (lncRNA) is one of the important kinds of ncRNA. Previous studies have shown that various lncRNAs are involved in the progression of cancer. LncRNA plasmacytoma variant translocation 1 (PVT1) is a newly discovered oncogenic factor that has been confirmed to be overexpressed in many ...

Active: 2021-02-02

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Mortalin promotes breast cancer malignancy - ScienceDirect

Mortalin promotes EMT progression in breast cancer. EMT is a process in which malignant epithelial cells transition to cells with a mesenchymal morphology. This can increase the potential for transfer of cancer cells,(Chakraborty et al., 2020) which can prelude the establishment and development of cancer.

Active: 2021-02-11

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Senescence Reprogramming by TIMP1 Deficiency Promotes ...

Guccini et al. show that TIMP1 loss switches senescence from a tumor-suppressive to a pro-metastatic process in prostate cancer mouse models. Pharmacological targeting of TIMP1-deficient senescent tumor cells impedes metastases in mice, thereby validating the therapeutic potential of senolytic therapy in prostate cancer.

Active: 2021-03-01

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AIRE is induced in oral squamous cell carcinoma and ...

Autoimmune regulator (AIRE) is a transcriptional regulator that is primarily expressed in medullary epithelial cells, where it induces tissue-specific antigen expression. Under pathological conditions, AIRE expression is induced in epidermal cells and promotes skin tumor development. This study aime …

Active: 2021-02-03

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Cysteine transporter SLC3A1 promotes breast cancer ...

Collectively, our data demonstrate that SLC3A1 promotes cysteine uptake and determines cellular response to antioxidant N-acetylcysteine, suggesting SLC3A1 is a potential therapeutic target for breast cancer. Keywords: solute carrier SLC3A1, breast cancer, ROS, cysteine, PDK1.

Active: 2021-03-02

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Jill Biden promotes 2 passions: military and cancer ...

Her and President Joe Biden s son Beau was a Delaware Army National Guard member who spent a year in Iraq from 2008 to 2009. He died of brain cancer in 2015 at age 46.

Active: 2021-02-02

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Cancer-associated adipocyte-derived G-CSF promotes breast ...

Li Liu, Yudong Wu, Cheng Zhang, Chong Zhou, Yining Li, Yi Zeng, Chunbo Zhang, Rong Li, Daya Luo, Lieliang Wang, Long Zhang, Shuo Tu, Huan Deng, Shiwen Luo, Ye-Guang Chen, Xiangyang Xiong, Xiaohua Yan, Cancer-associated adipocyte-derived G-CSF promotes breast cancer malignancy via Stat3 signaling, Journal of Molecular Cell Biology, Volume 12, Issue 9, September 2020, Pages 723–737, https ...

Active: 2021-02-27

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American Cancer Society | Information and Resources about ...

Dedicated to helping people who face cancer. Learn about cancer research, patient services, early detection, treatment and education at cancer.org.

Active: 2021-03-01

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[Full text] GSG2 Promotes Development and Predicts Poor ...

Introduction. Ovarian cancer is one of the most common malignant tumors in gynecology. The incidence of ovarian cancer ranks third, while the mortality rate is the highest among female malignant tumors of the reproductive system. 1 Ovarian cancer has the characteristics of concealed onset, high malignancy, and easy metastasis, which causes its poor prognosis. 2 Although early-stage ovarian ...

Active: 2021-03-01

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Zhongchao Inc. Promotes Standardized Liver Cancer ...

The Guidelines will undergo a new round of update in 2021 to meet the demand of rapid developments in liver cancer diagnosis and treatment in recent years. Zhongchao's job is to utilize its ...

Active: 2021-02-27

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Jill Biden promotes two passions: military families and ...

News. U.S. Jill Biden promotes two passions: military families and cancer research. President Joe Biden and first lady Jill Biden pay their respects to the late U.S. Capitol Police officer Brian ...

Active: 2021-02-01

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